Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0312145
PubChem CID
Molecular Formula
C10H7NO4
Molecular Weight
205.169 g/mol
Synonyms/Alias
[xanthurenic acid; 59-00-7; 4;8-Dihydroxyquinoline-2-carboxylic acid; Xanthuric acid; 8-Hydroxykynurenic acid; Xanthurenate; 4;8-Dihydroxyquinaldic acid; 4;8-Dihydroxyquinaldinic acid; 8-hydroxy-4-oxo...
InChI Key
FBZONXHGGPHHIY-UHFFFAOYSA-N
InChI
InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15)
IUPAC Name
8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid
CAS Number
59-00-7

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

22 23 0 0 0 0 0 0 0 0999 V2000
-3.0231 -0.9338 0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.8854 -1.7411 0.0102 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.6038 -1.160...

Experimental Data

Activity Data

Target Ion Channel
Aquaporin-1
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 1000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
37 °C
Test Method
Spheroid Spreading Assay
Test Species
Not specified

Binding Information

Binding Site
Transmembrane domain
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
15
Rotatable Bonds
1
logP
0.9319
Complexity
53.1928
TPSA (Ų)
90.39
H-Bond Donors
3
H-Bond Acceptors
3
Ring Count
2
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